Starting a family can feel like an emotional roller coaster ride. If you’re struggling to conceive, finding the right clinical support makes all the difference.
No matter your path, the best fertility clinics in Philadelphia provide top-tier care, modern labs, and an inclusive space for every single family planner. Let’s look at the top options to help you start your parenting journey today with total confidence.
You might also be looking for a holistic route with a local naturopath or need serious medical guidance, like seeing an orthopedic specialist for joint care during pregnancy.
How much does fertility treatment cost in Philadelphia?
Fertility treatments in the city vary wildly depending on your specific medical requirements and choice of provider.
| Service Type | Estimated Cost Range |
| Initial Consultation | $200 – $500 |
| Diagnostic Testing | $1,000 – $3,000 |
| Base In Vitro Fertilization (IVF) Cycle | $12,000 – $19,000 |
| Economic IVF Packages | Starts at $5,495 |
| Fertility Medications | $4,000 – $7,000 |
| Specialized Add-Ons (Intracytoplasmic Sperm Injection – ICSI, Preimplantation Genetic Testing for Aneuploidies – PGT-A, Freezing) | Additional fees apply |
1. Main Line Fertility

Website: https://www.mainlinefertility.com/
Address: 1650 Arch Street, Suite 1907
Contact: (610) 527-0800
Hours: Monday – Thursday: 8:00AM – 4:00PM, Friday: 8:00AM – 3:30PM
Main Line Fertility brings over thirty years of regional experience to the table, offering highly personalized plans.
Their network provides everything from In Vitro Fertilization (IVF) to inclusive LGBTQ+ care backed by a College of American Pathologists (CAP) accredited lab.
They also offer wonderful holistic support, including emotional wellness resources and nutrition guidance.
Their exceptional medical expertise and multiple convenient neighborhood offices keep them high on our list. They truly tailor care to your personal family-building goals instead of using a standard protocol.
The clinical team is highly decorated, but the office side needs some serious work. I talked to a local couple who loved the medical staff but faced major billing headaches and surprise insurance issues.
Communication gaps regarding out-of-pocket costs left them feeling quite frustrated. You might also encounter long wait times during routine blood draws.
Listened to all of my concerns and gave an individualized care plan
I love how informative and kind everyone at main line fertility is. They take their time and listened to all of my concerns and gave an individualized care plan. Sydney is so nice and so sweet, she has explained everything in detail and takes the time to make sure I understood each step and was comfortable with the plan moving forward! Thank you MLF
Dominique Johnson | Google Review
Goes above and beyond in making you feel comfortable, supported
Infertility is an experience that can be really lonely, frustrating, difficult, and hard to manage. Main Line Fertility goes above and beyond in making you feel comfortable, supported, and understood. From care that is personalized to your specific needs, to the incredible staff who always takes the time to answer your questions, I was beyond impressed with Main Line Fertility – and am so grateful I chose them as my partners in this journey.
Ashley Waters | Google Review
2. RMA Philadelphia | Center City

Website: https://rmanetwork.com/our-locations/rma-philadelphia/philadelphia-pa/
Address: 1015 Chestnut Street, 8th Floor
Contact: (215) 922-1556
Hours: Monday – Friday: 7:00AM – 4:00PM
Data-driven individuals will appreciate a team that prioritizes hard science above all else. RMA Philadelphia centers its entire care model on advanced reproductive research and exceptional IVF success rates.
As part of a massive physician-led network, they offer full-service treatments alongside their high-tech Artemis patient portal for easy tracking. This setup helps you stay fully updated on your results throughout your entire journey.
However, a heavy focus on data can sometimes make the process feel a bit mechanical. Some patients note a lack of individualized planning, feeling like they are on a standard protocol rather than a custom path.
On top of that, getting your medical records can involve annoying administrative delays. Communication between different administrative teams can also feel a bit disconnected.
You might also have to travel to their suburban offices for specific weekend procedures, which isn’t always clear up front. But their deep laboratory infrastructure and high financial network integrations make them hard to beat.
I feel incredibly blessed
Absolutely amazing experience. RMA took a complicated and stressful process and made it as manageable and smooth as possible. We were successful in conceiving on our first try. Can’t say enough good things. I feel incredibly blessed for having found RMA, having previously worked with another fertility center that was highly lacking.
Marcie McBride | Google Review
Amazing at answering every single question I had
I love RMA. Not only are they very responsive and kind, but they are thorough with their process. I switched over to RMA after 5 failed IUIs at Penn Fertility. I am now pregnant after ONE iui at RMA! They closely monitored me and were amazing at answering every single question i had.
If anyone is struggling at a different clinic, please consider switching to RMA.
Update: pregnant a second time (this time using IVF) and pregnant on the first try with RMA. they are like family now 🙂
Devon Johnston | Google Review
3. Shady Grove Fertility in Philadelphia

Website: https://www.shadygrovefertility.com/locations/pennsylvania/philadelphia-fertility-center/
Address: 1515 Market Street, Suite 1030
Contact: (610) 667-1070
Hours: Monday – Friday: 7:00AM – 4:00PM
If you want the backing of America’s largest fertility network, this Center City office is a top choice. Shady Grove Fertility brings unmatched clinical experience to the table, boasting over one hundred thousand babies born nationwide.
They provide a massive IVF ecosystem and famous financial options like their shared-risk one-hundred percent refund program. These setups work wonders for reducing the financial anxiety of treatment.
Their high success rates and wide insurance acceptance mean you’re getting top-tier clinical care. Plus, they have a collaborative physician model that ensures multiple experts review your case for the best possible results.
But operating at such a massive scale can sometimes compromise the personal touch. During my own consultation at their office, the appointment felt rushed, and the staff’s communication felt pretty impersonal.
It can feel a bit like you’re just another case number instead of a person. Also, you might need to push hard to get a thorough explanation of all your treatment paths.
Helped to turn our whole fertility journey around
Jordan (RN) has been our guardian angel during this challenging experience. She has phenomenal communication, empathy and professionalism which helped to turn our whole fertility journey around. I feel eternally grateful to have had her on my care team!
No matter how early in the morning it is, Brooke always has a smile on her face and has gone above and beyond to make me feel comfortable. She is consistently a bright spot during my monitoring and is the best “stick” at SGF!
Hana Bernett | Google Review
Incredibly caring and supportive
I don’t have enough good things to say about the SGF center city clinic. This is my second time with them and the staff are so incredibly caring and supportive. They’re also very fast with their response times and I’ve never waited longer than 10 minutes to be seen (and am usually seen immediately). Dr. Kallen is also incredible. Really grateful for the care at this center, and can’t recommend them enough.
Abinaya Chandar | Google Review
4. CCRM Fertility of Philadelphia

Website: https://www.ccrmivf.com/
Address: 822 Pine St, Suite 4B
Contact: (215) 829-8110
Hours: Monday – Friday: 8:30AM – 4:30PM
Overcoming complex reproductive challenges often requires cutting-edge clinical innovation.
CCRM Fertility of Philadelphia is a global leader in advanced fertility science, utilizing proprietary lab protocols designed to help patients achieve pregnancy in fewer cycles.
Their Center City team features fellowship-trained specialists who leverage top-tier in-house embryology and genetic testing setups. This research-driven approach gives hope to many complex cases.
The medical side is highly sophisticated, but navigating the administrative side can be frustrating. Patients often face a complete lack of upfront pricing transparency during their initial visits, with financial breakdowns delayed for weeks.
You might also find the initial consultation to be incredibly information-heavy without offering clear, actionable next steps. Phone follow-ups can also go unanswered. Plus, expect to book multiple appointments before you get a fully finalized treatment plan.
However, their superior live birth rates and elite laboratory standards make the administrative hurdles well worth it for most families.
The compassion, flexibility, and professionalism
I was a patient of Dr. Kelly’s for 2 years and ultimately needed to do IVF for multiple miscarriages. Everyone’s ‘fertility journey’ is different, but the compassion, flexibility, and professionalism of Dr. Kelly, Stephanie, Beth and all other staff, was amazing. This is not a cookie-cutter, big box medical system clinic. They have a personal touch. I really felt like they were family. They helped to make me a mom and for that, I will be forever grateful. I would recommend Dr. Kelly and all the other lovely ladies there, to anyone who needs help growing her family.
Gina Simoncini | Google Review
The nicest and friendliest practitioners
Dr Kelly and Beth are not only experts in fertility and total family building though also the nicest and friendliest practitioners. As a same sex couple seeking to find options to build our family, they embrace that each family builds their family differently. We can not be any more satisfied and glad we were recommended Dr Kelly and her practice.
Chip Malloy| Google Review
5. Fertility Home Care

Website: https://fertilityhc.com/
Address: 1411 S Darien St
Contact: [email protected]
Hours: Available 24/7 (In-home and virtual service)
Managing the intense stress of daily medication schedules can be the hardest part of fertility care. Fertility Home Care offers a unique solution by sending trained registered nurses straight to your house to administer vital injections.
This specialized service provides personalized training and flexible support for everything from a full cycle to a single trigger shot. It completely changes the game for self-injection anxiety.
The peace of mind this service offers is unmatched for anxious parents-to-be. Their expert team includes licensed pharmacists who ensure your medications are handled perfectly every single time.
But because they rely on a mobile network of professionals, their availability depends heavily on nurse scheduling and local coverage capacity. This can limit your flexibility during peak treatment windows.
So, booking your preferred time slot requires some advanced planning. But their stellar independent reviews and highly compassionate approach prove they’re worth every penny for ultimate stress relief during an IVF cycle.





